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. 2021 Jan 12;57(2):191–206. doi: 10.1007/s11626-020-00532-8

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© The Author(s) 2021

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Figure 4. — Brain organoids rely on self-assembly during differentiation from pluripotent cells. Adjusting culture conditions has produced large organoids exhibiting self-organized internal structure as well as organoids representing distinct brain regions. Adapted from Qian et al. (2016), with permission from Elsevier.