Table 4.
Correlation between family history of diabetes and clinical characteristics
| Parental history of DM | Sibling history of DM | |||||||
| r | P | a-r | a-P | r | P | a-r | a-P | |
| Sex | 0.046 | 0.171 | −0.134 | <0.001 | ||||
| Age | −0.237 | <0.001 | 0.125 | <0.001 | ||||
| SBP | −0.031 | 0.357 | −0.031 | 0.357 | −0.037 | 0.266 | −0.034 | 0.319 |
| DBP | 0.032 | 0.334 | 0.002 | 0.958 | −0.015 | 0.653 | −0.002 | 0.951 |
| BMI | 0.06 | 0.077 | −0.088 | 0.01 | ||||
| TG | 0.075 | 0.028 | 0.026 | 0.45 | −0.018 | 0.6 | 0.011 | 0.753 |
| TC | 0.07 | 0.041 | 0.054 | 0.125 | 0.038 | 0.273 | 0.045 | 0.204 |
| HDL | −0.063 | 0.066 | −0.04 | 0.256 | 0.019 | 0.581 | −0.031 | 0.383 |
| LDL | 0.045 | 0.179 | 0.03 | 0.376 | −0.011 | 0.741 | −0.021 | 0.542 |
| FBG | 0.141 | <0.001 | 0.119 | 0.001* | 0.054 | 0.109 | 0.075 | 0.028 |
| HbA1C | 0.101 | 0.003 | 0.071 | 0.038 | 0.005 | 0.87 | 0.01 | 0.777 |
| HOMA2-IR (%) | −0.022 | 0.521 | −0.039 | 0.275 | −0.015 | 0.673 | 0.008 | 0.83 |
| HOMA2-B (%) | −0.093 | 0.007 | −0.066 | 0.061 | −0.07 | 0.044 | −0.096 | 0.007 |
| DKA | 0.079 | 0.019 | 0.05 | 0.146 | 0.03 | 0.369 | 0.05 | 0.142 |
a-r and a-p: correlation adjusted for sex, age and BMI.
HOMA2-B and HOMA2-IR were applied to estimate the function of β-cell and insulin resistance, respectively, which were calculated using fasting plasma glucose and C-peptide.
*Refers to p<0.05.
BMI, body mass index; DBP, diastolic blood pressure; DKA, diabetic keto acidosis; DM, diabetes mellitus; FBG, fasting blood glucose; HbA1C, glycosylated haemoglobin; HDL, high-density lipoprotein; HOMA2-B, homoeostatic model assessment 2-B; HOMA2-IR, homoeostatic model assessment 2-insulin resistance; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure; TC, total cholesterol; TG, triglyceride; WHR, waist-to-hip ratio.