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. 2021 Jan 8;14:27–39. doi: 10.2147/IJGM.S275016

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© 2021 Yin and Lin.

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MiR-21 is up-regulated in CSCC tissues and cells. (A) Microarray-based analysis of up-regulated miRNAs in tumor tissues (n =3); (B) RT-qPCR of miR-21 expression in tumor tissues and adjacent tissues (n = 56, *P < 0.05 according to the paired t-test); (C) Overall survival of CSCC patients (cut-off value of 4.37) with miR-21 high expression and low expression (n = 56, according to Kaplan-Meier analysis); (D) RT-qPCR of miR-21 expression in HaCaT, HSC-1 and A431 cells (*P < 0.05 according to the one-way ANOVA).