Table 6.

Correlations Between DPP4 Activities, BDNF, SIRT-1, Celluar Oxidative Stress, and Apoptosis vs Relative Expression of miRNAs in Older Adults with MCI

Characteristics	miRNAs Relative Expressiona
	miR-124a		miR-483-5p		miR-142-3p		miR-125b
	r	P	r	P	r	P	r	P
DPP4 activity (nmol/min/mL)	0.12	<0.01	0.24	<0.002	0.38	< 0.002	0.145	<0.001
BDNF (ng/mL)	0.21	<0.01	0.31	<0.01	0.28	< 0.01	0.31	<0.001
SIRT1(ng/mL)	0.45	<0.01	0.57	<0.01	0.49	< 0.01	0.49	<0.01
NO	0.37	<0.001	0.42	<0.001	0.36	< 0.001	0.76	<0.001
MDA	0.18	<0.001	0.23	<0.001	0.42	< 0.001	0.27	<0.001
CAT	−0.51	<0.001	−0.62	<0.001	−0.54	< 0.001	−0.63	<0.001
SOD	−0.85	<0.001	−0.82	<0.001	−0.47	< 0.001	−0.84	<0.001
Bax	−0.45	<0.001	−0.36	<0.001	−0.56	< 0.001	−0.46	<0.001
Bcl-2	−0.17	<0.001	−0.42	<0.001	−0.68	< 0.001	−0.91	<0.001
Caspase-3	−0.75	<0.001	−0.53	<0.001	−0.47	< 0.001	−0.43	<0.001

Note: ^aP-value determined by partial correlation analysis with respect to the DPP4 activity, BDNF, DBR, cellular oxidative stress, and apoptosis adjusted for age, BMI, gender, education level, exercise levels, and working among older adults with MCI.