Table 2.
Hazard ratios of the uric acid for incident hypertension.
| no.of events | Unadjusted |
Model1 |
Model2 |
|
|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | HR (95% CI) | ||
| Continuous | ||||
| total n = 12029 | 1457 | 1.27 (1.23–1.32)* | 1.21 (1.15–1.27)* | 1.14 (1.09–1.20)* |
| Categorical | ||||
| Q1 (n = 3406) | 334 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) |
| Q2 (n = 2869) | 295 | 1.05 (0.90–1.23) | 1.05 (0.90–1.23) | 0.98 (0.84–1.15) |
| Q3 (n = 2893) | 365 | 1.30 (1.12–1.51)* | 1.33 (1.15–1.54)* | 1.21 (1.04–1.41)† |
| Q4 (n = 2861) | 463 | 1.72 (1.50–1.98)* | 1.74 (1.51–2.00)* | 1.44 (1.25–1.67)* |
Hazard ratios are indicated per 1 mg/dl increase for continuous uric acid level, and each quartile compared to lowest quartile. Adjustment was performed for the following risk factors: model 1 = adjusted for age, gender, height, and weight; model 2 = model 1 + systolic blood pressure, diabetes, smoking, LDL cholesterol, HDL cholesterol, and eGFR.
Q1 indicates lower quartile for uric acid; Q4, highest quartile; HR, hazard ratio; other abbreviation as in Table 1.
*p < 0.001, †p < 0.05.