Table 3.
Age stratified analysis for the association of UA with incident hypertension in men and women.
| n | no. of incident hypertension | HR | 95%CI | p | ||
|---|---|---|---|---|---|---|
| Male | ||||||
| Total | 7,112 | 1,057 | 1.1 | 1.04 | 1.17 | <0.001 |
| age subgroups | ||||||
| <40 years | 1,769 | 148 | 1.14 | 0.98 | 1.32 | 0.084 |
| 40-50 years | 2,654 | 378 | 1.17 | 1.07 | 1.28 | 0.001 |
| 50-60 years | 1,881 | 360 | 1.07 | 0.96 | 1.19 | 0.201 |
| ≧60 years | 808 | 171 | 1.03 | 0.9 | 1.18 | 0.686 |
| Female | ||||||
| Total | 4,917 | 400 | 1.23 | 1.1 | 1.38 | <0.001 |
| age subgroups | ||||||
| <40 years | 937 | 31 | 1.05 | 0.66 | 1.67 | 0.66 |
| 40-50 years | 1,902 | 130 | 1.29 | 1.07 | 1.56 | 0.009 |
| 50-60 years | 1,436 | 148 | 1.21 | 1 | 1.47 | 0.053 |
| ≧60 years | 642 | 91 | 1.34 | 1.04 | 1.73 | 0.023 |
Hazard ratios are indicated per 1 mg/dl increase for uric acid level. Adjustment was performed for the following risk factors: model 1 = adjusted for age, gender, height, and weight; model 2 = model 1 + systolic blood pressure, diabetes, smoking, LDL cholesterol, HDL cholesterol, and eGFR.
Q1 indicates lower quartile for uric acid; Q4, highest quartile; HR, hazard ratio; other abbreviation as in Table 1.