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. 2020 Apr 15;5:100029. doi: 10.1016/j.ijchy.2020.100029
Highlights Class of Recommendation Level of Evidence
  • PA entails a heterogeneous group of common sporadic forms and rarer familial forms.

I A
  • Its prevalence varies according to the cohort of hypertensive patients studied, on the whole between 5.9% and 20%.

I B
  • Familial forms are rare and mostly characterized by autosomal dominant transmission.

I A
  • Sporadic forms comprise surgically curable unilateral causes (aldosterone-producing adenoma and unilateral hyperplasia) and medically treatable bilateral adrenal hyperplasia.

I A
  • Despite the high prevalence of PA only 1–2% of hypertensive patients are screened for it.

II B