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. 2020 Apr 15;5:100029. doi: 10.1016/j.ijchy.2020.100029
Highlights Class of Recommendation Level of Evidence
  • Hypokalemia and/or severe hypertension during pregnancy, especially before week 20, should raise suspicion of PA.

I B
  • Diagnosis is based on high ARR values and can be confirmed by testing for FH or by MRI.

I B
  • If the diagnosis of APA is already known surgery is recommended before starting pregnancy.

IIb B
  • When BP is not controlled with treatment, laparoscopic adrenalectomy is preferred in APA patients during the second trimester and MRAs might be added only if hypertension is uncontrolled.

IIa C