Table 2.
OCT and OCT-A parameters in the macular retina in affected eyes of NAION.
| Affected | Baseline (n = 21) | 1∼2 w (n = 21) | 1∼2 m (n = 21) | 3∼6 m (n = 13) | p a value | |
|---|---|---|---|---|---|---|
| GCC (μm) () | wGCC | 103.67 ± 6.95 | 99.48 ± 7.69 | 89.24 ± 6.66 | 80.62 ± 8.62 | ≤0.001∗ |
| sGCC | 102.67 ± 7.91 | 95.52 ± 8.80 | 84.62 ± 7.72 | 74.62 ± 9.46 | ≤0.001∗ | |
| iGCC | 104.62 ± 7.34 | 103.48 ± 8.80 | 93.85 ± 7.72 | 86.54 ± 10.37 | ≤0.001∗ | |
| p si value | 0.114 | 0.001∗ | ≤0.001∗ | 0.002∗ | — | |
|
| ||||||
| SVD (%) () | wSVD | 46.07 ± 2.09 | 43.70 ± 2.39 | 41.10 ± 2.63 | 37.16 ± 3.77 | ≤0.001∗ |
| sSVD | 46.19 ± 2.16 | 43.91 ± 2.43 | 40.32 ± 3.12 | 36.92 ± 3.89 | ≤0.001∗ | |
| iSVD | 45.89 ± 2.30 | 43.63 ± 2.73 | 41.75 ± 2.47 | 36.88 ± 4.06 | ≤0.001∗ | |
| wDVD | 45.82 ± 2.96 | 45.37 ± 3.68 | 46.99 ± 2.39 | 47.44 ± 3.35 | 0.075 | |
| p si value | 0.149 | 0.626 | 0.010∗ | 0.807 | — | |
| Unaffected | (n = 19) | (n = 19) | (n = 19) | (n = 13) | p a value | |
| wGCC | 106.68 ± 7.61 | 107.58 ± 6.63 | 106.79 ± 7.22 | 106.92 ± 7.51 | 0.971 | |
| wSVD | 45.49 ± 1.97 | 45.52 ± 1.87 | 45.44 ± 1.89 | 45.41 ± 1.67 | 0.999 | |
| wDVD | 47.60 ± 3.20 | 47.64 ± 2.89 | 47.67 ± 3.02 | 46.94 ± 2.66 | 0.876 | |
| p b value | 0.304 | 0.002∗ | ≤0.001∗ | ≤0.001∗ | — | |
| P c value | 0.444 | 0.008∗ | ≤0.001∗ | ≤0.001∗ | — | |
| P d value | 0.121 | 0.044∗ | 0.673 | 0.600 | — | |
NAION, nonarteritic anterior ischemic optic neuropathy. wGCC (μm), average ganglion cell complex thickness. wSVD (%), average superficial vessel density. wDVD (%), average deep vessel density. s/iGCC (μm), superior- and inferior-hemi thickness of macular ganglion cell complex. s/iSVD (%), s/iDVD(%), superior- and inferior-hemi values of superficial and deep vessel density. psi, p value for comparison of superior- and inferior-hemi values using the Wilcoxon test. pa, p value obtained using the nonparametric Kruskal–Wallis test for evaluating the overall differences among four intervals. pb/pc/pd, p values for comparison of wGCC/wSVD/wDVD values in affected subjects versus unaffected eyes using the Wilcoxon test. ∗p value<0.05 was considered statistically significant.