Table 2.

Parameters of the LC-QTOF-MS/MS system.

Specification	Setting
Column	Raptor ARC-18 column with dimensions of 2.7 μm (particle size), 2.1 mm (internal diameter), 100 mm (length) and 90 Å (pore size) (Restek, Bellefonte, USA
Injection volume	5 μL
Operating	Reverse phase ultra-high-performance liquid chromatography (RP-UHPLC)
Capillary voltage at	4.5 kV
End plate offset	−500 V
Dry heater nebulizer gas pressure	1.8 bar
Scan	50 to 1300 m/z