Table 2.
Skin irritation score after different concentrations of polychaete ointment (PO) applied on intact skin over period of time. Concentrations of PO were 0.1%, 0.5%, and 1.0%. Cetomacrogol emulsifying ointment was used as negative control. No signs of skin irritation (oedema and erythema) were observed for all the tested ointments.
| Skin reaction | Observation time (hr) | Treatment | Total score | |||
|---|---|---|---|---|---|---|
| Negative control | 0.1% PO | 0.5% PO | 1.0% PO | |||
| Erythema formation | 1 | 0 | 0 | 0 | 0 | 0 |
| 24 | 0 | 0 | 0 | 0 | 0 | |
| 48 | 0 | 0 | 0 | 0 | 0 | |
| 72 | 0 | 0 | 0 | 0 | 0 | |
|
| ||||||
| Oedema formation | 1 | 0 | 0 | 0 | 0 | 0 |
| 24 | 0 | 0 | 0 | 0 | 0 | |
| 48 | 0 | 0 | 0 | 0 | 0 | |
| 72 | 0 | 0 | 0 | 0 | 0 | |