Table 6:

Comparative characteristics of the cytokine profile at day 0 of the research and control group (Me, 0.5 L; 0.5 U) (Q1;Q3).

Indicator	Research group (n=130)	Control group (n=25)	P-value (between groups)
UA, mmol/l	459 (399;536)	276 (234;283)	0.000001
Blood CRP, mg/l	11.9 (6;24)	1.3 (0.9;1.7)	0.000001
IL-1b, pg/ml	128 (127;129)	23 (21;24)	0.000001
IL-6, pg/ml	214 (212;215)	22 (21;24)	0.000001
IL-8, pg/ml	43 (43;43)	24 (23;24)	0.000001
TNF-α, pg/ml	121 (121;122)	25 (24;25)	0.000001
IL-10, pg/ml	72 (71;73)	23 (21;23)	0.000001