FIGURE 1.

$\mathrm{Log}10(\mathrm{p})$ probability of urinary COL1A1 fragments associated with heart failure death in the multivariable Cox regression model in 354 patients. There are 33 heart failure deaths. The model was adjusted for age, sex, body mass index, history of ischemic disease, heart rate, and serum creatinine. The fragments were allocated according to their start position on COL1A1. The two horizontal lines denote the significance thresholds at P = .01 and P = .05, respectively. Only significant fragments (P < .05) were colored and annotated. Fragments that were increased in heart failure deaths were colored in red, otherwise in blue