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. 2021 Jan 5;2021:8899143. doi: 10.1155/2021/8899143

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Copyright © 2021 Eman A. Ahmed et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Photomicrographs of (H & E 200×) stained sections of right hind leg ankle joints show histopathological effects of BM-MSCs and/or IMC treatments on CFA-induced arthritic rats. Ankle joint section from normal rat (a) shows normal structure of the synovial membrane (s), cartilage (c), and bone (b). Ankle joint section from CFA-induced arthritic rat (b) shows the substantially expanding synovial membrane with sever pannus formation (p). Ankle joint section from CFA + BM-MSCs rat (c) shows the synovial membrane with mild infiltration and pannus formation (p). Ankle joint section from CFA + IMC rat (d) shows moderate infiltration and pannus formation. Ankle joint section from CFA + BM-MSCs plus IMC rat (e) shows nearly normal histological structure of the hind ankle joint with a normal synovial membrane and mild cellular infiltration.