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. 2021 Jan 4;77(2):376–382. doi: 10.1161/HYPERTENSIONAHA.120.16191

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© 2020 The Authors.

Hypertension is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure 1. — Genetic proxies of blood pressure and risk of atrial fibrillation. A, Two-sample Mendelian randomization using an inverse-variance weighted model was created using a genetic instrument associated with a 10-mm Hg increase in systolic blood pressure (SBP), diastolic blood pressure (DBP), and pulse pressure (PP) and risk of atrial fibrillation. B, A median weighted model was created as a sensitivity analysis. Figures are expressed as odds ratios (ORs), 95% CIs, and P for Mendelian randomization estimates. SNP indicates single-nucleotide polymorphism.