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. 2020 Nov 25;49(2):e179–e190. doi: 10.1097/CCM.0000000000004770

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Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine and Wolters Kluwer Health, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 5. — Changes in systemic hemodynamics and renal function in response to megadose sodium ascorbate (Na Asc) treatment in one septic patient with a severe case of coronavirus disease 2019 (n = 1). Norepinephrine dose (A), oxygen tension (Po₂) (filled squares) and inspired oxygen fraction (open circles) (B), mean arterial pressure (C), serum creatinine (D), heart rate (E), and urine output (F) are presented at pretreatment (time 0), after a 30-min infusion of Na Asc bolus therapy (BT, 30 g), and then at hourly intervals during an infusion of Na Asc for 6.5 hr (4.6 g/hr).