Table 3. Hemodynamics in vitro experiments.
| Group | T0 | T1 | T2 | T3 | T4 | |
| HR (min-1) | SHAM | 262 ± 16 | 250 ± 22 | 248 ± 10 | 246 ± 22 | 235 ± 32 |
| IR | 258 ± 17 | 198 ± 14*# | 173 ± 12*# | 150 ± 9*# | 124 ± 12*# | |
| SPC | 260 ± 11 | 213 ± 7*#& | 198 ± 10*#& | 180 ± 18*#& | 156 ± 19*#& | |
| SPC+DMSO | 264 ± 21 | 211 ± 6*#& | 193 ± 11*#& | 180 ± 7*#& | 157 ± 18*#& | |
| SPC+OSMI-1 | 265 ± 20 | 205 ± 9*# | 158 ± 12*# | 144 ± 15*# | 137 ± 13*# | |
| LVSP (mmHg) | SHAM | 110 ± 5 | 108 ± 7 | 102 ± 10 | 96 ± 5 | 94 ± 9 |
| IR | 115 ± 12 | 64± 6*# | 48 ± 6*# | 44 ± 4*# | 35 ± 4*# | |
| SPC | 106 ± 18 | 93 ±5*#& | 81 ±6*#& | 64 ± 4*#& | 59 ± 4*#& | |
| SPC+DMSO | 110 ± 11 | 91 ± 6*#& | 85 ± 4*#& | 66 ± 6*#& | 58 ± 6*#& | |
| SPC+OSMI-1 | 109 ± 12 | 69 ± 4*# | 53 ± 7*# | 45 ± 7*# | 35 ± 4*# | |
| LVEDP (mmHg) | SHAM | 6.7 ± 0.8 | 7.2 ±0.6 | 7.3 ± 0.5 | 7.4 ± 0.5 | 7.6 ± 1.1 |
| IR | 7.0 ± 0.2 | 37.6 ± 2.3*# | 42.1 ± 3.7*# | 47.3 ± 1.9*# | 51.7 ± 4.2*# | |
| SPC | 7.4 ± 0.6 | 21.6 ± 1.9*#& | 25.9 ± 2.1*#& | 29.2 ± 1.1*#& | 31.6 ± 1.9*#& | |
| SPC+DMSO | 7.0 ± 0.4 | 23.5 ± 1.5*#& | 27.7 ± 3.4*#& | 29.8 ± 0.8*#& | 31.7 ± 2.1*#& | |
| SPC+OSMI-1 | 6.6 ± 0.6 | 38.5 ± 2.7*# | 42.1 ± 4.5*# | 45.0 ± 1.8*# | 51.4 ± 5.8*# | |
| +dp/dtmax (mmHg/s) | SHAM | 2330 ± 218 | 2272 ±203 | 2159 ± 92 | 2008 ± 192 | 1924 ± 158 |
| IR | 2188 ± 183 | 1853 ± 174*# | 1586 ± 93*# | 1358 ± 157*# | 1145 ± 79*# | |
| SPC | 2281 ± 239 | 2160 ± 164*#& | 2067 ± 202*#& | 1786 ± 156*#& | 1457 ± 107*#& | |
| SPC+DMSO | 2293 ± 261 | 2078 ± 185*#& | 2001 ± 169*#& | 1748 ± 234*#& | 1542 ± 144*#& | |
| SPC+OSMI-1 | 2324 ± 191 | 1927 ± 115*# | 1721 ± 145*# | 1383 ± 158*# | 1141 ± 131*# | |
| -dp/dtmax (mmHg/s) | SHAM | 2306 ± 228 | 2215 ±218 | 2158 ± 140 | 2087 ± 184 | 2053 ± 219 |
| IR | 2335 ± 213 | 1912 ± 89*# | 1418 ± 175*# | 1096 ± 72*# | 888 ± 64*# | |
| SPC | 2322 ± 173 | 2078 ± 301*#& | 1865 ± 87*#& | 1435 ± 159*#& | 1103 ± 99*#& | |
| SPC+DMSO | 2269 ± 137 | 2047 ± 139*#& | 1796 ± 199*#& | 1450 ± 111*#& | 1116 ± 77*#& | |
| SPC+OSMI-1 | 2376 ± 133 | 1864 ± 217*# | 1557 ± 228*# | 1024 ± 80*# | 901 ± 101*# |
*P < 0.05 vs T0; # P < 0.05 vs SHAM group; & P < 0.05 vs IR group. Values are means ± standard deviation. n = 6 /group. HR, heart rate; LVSP, left ventricular peak pressure; LVEDP, left ventricular end diastolic pressure; +dp/dtmax, maximal rate of the increase of left ventricular pressure; -dp/dtmax, maximal rate of the decrease of left ventricular pressure. T0, equilibration; T1, 30 min after reperfusion; T2, 60 min after reperfusion; T3, 90 min after reperfusion; T4, 2h after reperfusion. SHAM, sham control; IR, ischemia reperfusion; SPC, sevoflurane postconditioning; OSMI-1, the OGT inhibitor; DMSO, the OSMI-1 solvent.