Table 5. Results of haplotype analysis of five ABCB1 SNPs in CR and control groups.
Haplotype* | Frequency n (%) | P | OR (95%CI) | |
CR | NCR | |||
C G C G A | 26.78(0.042) | 42.98(0.051) | 0.456 | 0.828 (0.505~1.360) |
T A A A G | 20.89(0.033) | 14.85(0.017) | 0.053 | 1.924 (0.980~3.776) |
T A A G A | 29.78(0.047) | 36.67(0.043) | 0.718 | 1.096 (0.667~1.800) |
T A A G G | 165.44(0.262) | 185.45(0.218) | 0.05 | 1.282 (1.002~1.640) |
T A C A A | 33.67(0.053) | 27.79(0.033) | 0.05 | 1.667 (0.996~2.789) |
T G A G G | 40.77(0.065) | 79.64(0.094) | 0.04* | 0.663 (0.447~0.983) |
T G C A A | 143.43(0.227) | 208.64(0.245) | 0.388 | 0.896 (0.699~1.149) |
T G C G A | 32.44(0.051 | 59.72(0.070) | 0.132 | 0.713 (0.458~1.109) |
T G C G G | 63.03(0.100) | 91.22(0.107) | 0.626 | 0.919 (0.653~1.293) |
Abbreviation: CR, Clopidogrel resistance; OR, Odds ratio; CI, Confidence interval.
The order of SNPs in haplotypes: rs4148727, rs1045642, rs2032582, rs3789243, rs1858923.
*: P value <0.05 was considered as significant.