Table 1. Preponderant decreases of relative gene expression in LSK cells of middle-aged male compared with young male mice.
| Gene Symbol | Fold Regulation (> 2-fold) | P Value (< 0.05) |
| Lmo2 | 2.58 | 0.000353 |
| Angpt1 | 2.38 | 0.000148 |
| Flt3l | -2.01 | 0.045607 |
| Ccr1 | -2.07 | 0.046098 |
| Tlr3 | -2.27 | 0.049915 |
| Fut10 | -2.36 | 0.028103 |
| Lef1 | -2.6 | 0.014575 |
| Cd86 | -2.64 | 0.007944 |
| Il20 | -2.8 | 0.048758 |
| Kitl | -2.81 | 0.024654 |
| Il31ra | -3.12 | 0.032087 |
| Inhba | -3.13 | 0.032466 |
| Jag1 | -3.15 | 0.029 |
| Lrmp | -3.17 | 0.016812 |
| Hdac4 | -3.32 | 0.023868 |
| Ahsp | -3.38 | 0.033585 |
| Gata1* | -3.51 | 0.038088 |
| Pax5 | -3.58 | 0.015632 |
| Fzd1* | -3.73 | 0.02228 |
| Inha | -3.96 | 0.026484 |
| Tnfsf11 | -4.23 | 0.022865 |
| Trim10* | -5.03 | 0.015697 |
| Il10* | -5.82 | 0.012392 |
| Il1a* | -6.75 | 0.013767 |
| Il12b* | -6.99 | 0.011579 |
| Notch4* | -7.2 | 0.011783 |
| Il2* | -9.17 | 0.015044 |
| Dll1* | -10.17 | 0.008511 |
| Mal* | -10.65 | 0.010489 |
| Il25* | -11.1 | 0.007668 |
| Wnt3a* | -11.67 | 0.007274 |
| Il11* | -12.82 | 0.009566 |
*Also appears in Table 4.