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| Gene Symbol | Middle-aged vs Young | Old vs Young |
| Tlr3 | -2.27 | -3.08 |
| Cd86 | -2.64 | -3.52 |
| Trim10 | -5.03 | -8.73 |
| Fzd1 | -3.73 | -10.94 |
| Il25 | -11.1 | -18.58 |
