Table 1. Top-10 differential expressed genes in gastric cancer.
| The panel of DEGs in a gastric cell line of diffuse histological subtype ACP02: MYC-siRNA (2M) vs. Control-siRNA (2C) | ||||||||
| Downregulated | Upregulated | |||||||
| Gene Symbol | Log2FC | p-value | FDR | Gene Symbol | Log2FC | p-value | FDR | |
| UQCRH | -11.9 | 4.89E-38 | 2.70E-37 | ECT2 | 12.0 | 1.47E-58 | 1.35E-57 | |
| CDC25B | -11.6 | 6.73E-18 | 1.99E-17 | PSMC4 | 11.9 | 2.73E-24 | 9.98E-24 | |
| CYB561D2 | -11.4 | 2.30E-51 | 1.80E-50 | COL8A1 | 11.6 | 2.51E-31 | 1.15E-30 | |
| TTLL12* | -11.4 | 2.56E-147 | 1.06E-145 | PSMD11 | 11.3 | 8.94E-34 | 4.41E-33 | |
| ARHGAP1 | -11.3 | 3.00E-137 | 1.10E-135 | BFAR | 11.3 | 1.97E-26 | 7.73E-26 | |
| CDKN3* | -11.2 | 3.75E-29 | 1.61E-28 | YWHAE | 11.3 | 3.07E-06 | 5.30E-06 | |
| UBE2B | -10.9 | 7.22E-82 | 1.08E-80 | ABCF1 | 11.2 | 1.97E-26 | 7.72E-26 | |
| ATP6V0B | -10.9 | 2.09E-40 | 1.23E-39 | PGP | 10.9 | 1.06E-19 | 3.33E-19 | |
| CDC16* | -10.4 | 1.38E-49 | 1.03E-48 | TUSC3 | 10.3 | 1.22E-16 | 3.42E-16 | |
| UFD1L | -10.7 | 1.07E-48 | 7.79E-48 | CKAP2L | 10.2 | 1.01E-15 | 2.73E-15 | |
| The panel of DEGs in a gastric cell line of intestinal histological subtype ACP03: MYC-siRNA (3M) vs. Control-siRNA (3C) | ||||||||
| Downregulated | Upregulated | |||||||
| Gene Symbol | Log2FC | p-value | FDR | Gene Symbol | Log2FC | p-value | FDR | |
| PTPRA* | -12.0 | 2.33E-33 | 1.56E-31 | COX6A1 | 12.3 | 1.37E-16 | 1.91E-15 | |
| ATF1 | -11.9 | 7.33E-30 | 3.60E-28 | PA2G4 | 11.5 | 1.55E-49 | 2.66E-47 | |
| UBE2T* | -11.3 | 2.02E-07 | 8.82E-07 | ATP6V0C | 11.4 | 4.92E-15 | 5.77E-14 | |
| CINP | -10.9 | 2.97E-06 | 1.07E-05 | CIB1 | 11.3 | 4.21E-14 | 4.41E-13 | |
| TERF2 | -10.8 | 1.87E-16 | 2.56E-15 | NDUFA7 | 11.3 | 3.39E-08 | 1.67E-07 | |
| IK | -10.7 | 2.47E-10 | 1.61E-09 | TNFAIP3 | 11.2 | 2.39E-61 | 6.63E-59 | |
| MZT2B* | -10.7 | 4.34E-05 | 0.000133 | CDK2AP2 | 11.2 | 9.16E-19 | 1.64E-17 | |
| RAB23 | -10.6 | 7.94E-21 | 1.73E-19 | COX4I1 | 11.1 | 2.26E-10 | 1.49E-09 | |
| TPD52L2 | -10.5 | 4.82E-10 | 3.02E-09 | CCNB1 | 10.8 | 6.11E-21 | 1.35E-19 | |
| PSMD14 | -10.5 | 5.29E-08 | 2.54E-07 | RNF20 | 10.8 | 1.00E-37 | 9.01E-36 | |
Log2 FC [M/C] < 0: Downregulated (left panel); Log2 FC [M/C] > 0: Upregulated (right panel); FC: Fold change; FDR: False Discovery Rate.