OECT-based sucrose and glucose sensors
(A) Schematic of the OECT-based sucrose sensor. Gate (area = 300 μm ∗ 300 μm) is functionalized with three enzymes in order for sucrose to be converted to H2O2 that can then be oxidized at the PtNPs that are on the gate electrode.
(B) Typical transfer curve and transconductance of OECT device after functionalization with PtNPs for VSD = −0.4V and VSG from −0.2V to 1V.
(C) Sucrose sensor (orange) and glucose sensor (cyan) calibration curve in PBS buffer. Dashed lines represent fit to the sigmoidal function. Error bars represent the standard error, n = 8 devices for sucrose sensor and n = 5 devices for glucose sensor.
(D) Sucrose sensor response after 48hr of insertion in the tree for 100 μM and 300μM sucrose solutions (blue error bars represent the standard error for n = 3). In orange, the sucrose sensor calibration curve is shown for comparison. T test showed no statistical significance (p > 0.05) on the response of the sensors before and after 48hr implantation.