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. 2021 Jan 5;7(1):e05888. doi: 10.1016/j.heliyon.2020.e05888

Figure 6.

Figure 6

Effect of Le Carbone on hepatic HO-1, p47phox, Nrf2, p-JNK and p-ERK1/2 expression in NASH-HCC mice. Representative Western blots show specific bands for (A), HO-1; (B), p47phox; (C), Nrf2; (D), p-JNK (for JNK); (E), p-ERK1/2 (ERK1/2) and the representative histograms show the band densities with relative to GAPDH. Each bar represents mean ± SEM. Normal, age matched normal mice; NASH, untreated NASH-HCC mice; NASH + LC, NASH-HCC mice treated with Le Carbone suspension at 5 mg/mouse/day. Statistical analysis was carried out using One-way ANOVA followed by Tukey's test where, ∗p < 0.05, ∗∗p < 0.01 vs Normal, #p< 0.05, ##p < 0.01 and ###p < 0.001 vs NASH.