Table 2.

Risk of hepatocellular carcinoma according to baseline characteristics

	Number	HCC	Cumulative HCC incidence rate (%)			P
			3-yr	5-yr	7-yr
Age, yr						0.06
<50	298	1	0.0	0.0	0.9
50–59	520	12	1.5	2.0	3.1
≥60	422	10	1.0	1.5	4.8
Sex						0.07
Women	376	3	0.6	0.9	0.9
Men	824	20	1.2	1.6	4.1
Cirrhosisa						<0.001
No	1,035	9	0.4	0.6	1.6
Yes	165	14	4.6	6.5	13.3
ALT levels						0.35
Normal	1,015	18	1.0	1.3	2.9
Elevatedb	185	5	1.2	1.9	5.0
FIB-4						0.02
<1.45	603	9	0.4	0.9	3
1.45–3.25	525	10	1.4	1.4	2.5
>3.25	75	4	3.4	5.3	9.6
APRI						<0.001
<1	1,162	19	0.8	1.1	1.9
≥1	38	4	6.7	10.4	19.4
AVT						<0.001
No	984	12	0.7	0.9	2.2
Yes	216	11	2.5	3.9	8.1

^aCirrhosis was defined by radiologic evaluation for 1,147 patients and by elevated FIB-4 score (>3.25) for 53 patients.

^bElevated ALT levels were defined as ALT >34 in men or >30 in women.

ALT, alanine aminotransferase; APRI, aspartate aminotransferase to platelet ratio index; AVT, antiviral therapy; FIB-4, fibrosis 4; HCC, hepatocellular carcinoma.