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. 2020 Sep 30;14(6):1083–1092. doi: 10.1007/s12072-020-10093-3

Table 3.

Results of selected ROTEM tests, platelet counts and fibrinogen levels in patients stratified by severity of portal hypertensiona

HVPG
6–9 mmHg 10–19 mmHg ≥ 20 mmHg p-value
EXTEM CT (s) 77 [69–87] 74 [66–85] 75 [65–88] 0.656
EXTEM CFT (s) 126 [88–174] 128 [100–208] 132 [90–219] 0.804
EXTEM MCF (mm) 57 [50–65] 55 [46–59] 53 [44–60] 0.347
INTEM CT (s) 200 [167–233] 198 [169–222] 203 [180–227] 0.561
INTEM CFT (s) 103 [75–144] 110 [82–175] 114 [75–201] 0.653
INTEM MCF (mm) 55 [52–64] 55 [45–59] 52 [44–59] 0.271
FIBTEM MCF (mm) 13 [11–21] 14 [10–16] 14 [10–18] 0.921
Fibrinogen (mg/dl) 313 [201–373] 261 [216–324] 273 [209–341] 0.323
Platelets (G/µl) 141 [74–164] 99 [67–132] 96 [55–126] 0.173

aData are expressed as medians with interquartile range in square brackets. n = 21 (HVPG 6–9 mmHg), n = 84 (HVPG 10–19 mmHg, except n = 83 for platelet count), n = 54 (HVPG ≥ 20 mmHg). Data were analyzed using analysis of variance (ANOVA) with Tukey’s test for post hoc comparisons (EXTEM MCF, INTEM MCF and fibrinogen) or Kruskal–Wallis test with Dunn’s test for post hoc comparisons (remaining parameters). ROTEM, rotational thromboelastometry; HVPG, hepatic venous pressure gradient; EXTEM, extrinsic thromboelastometry; INTEM, intrinsic thromboelastometry; CT, clotting time; CFT, clot formation time; MCF, maximal clot firmness; FIBTEM, fibrinogen thromboelastometry