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. 2020 Nov 1;27(11):1160–1175. doi: 10.5551/jat.48843

Table 2. Hazard ratios for the cardiovascular risk prediction model with/ without Electrocardiogram.

Univariable with age adjustment Interaction P with sex Model with ECG Model without ECG

Multivariable Multivariable

HR (95% CI) HR (95% CI) HR (95% CI)
Men 1.76 (1.49, 2.08) 1.46 (1.21, 1.75) 1.46 (1.22, 1.76)
Age, years
    30–39 1.00 1.00
    40–49 0.418 2.26 (1.27, 4.03) 2.27 (1.27, 4.04)
    50–59 0.148 4.00 (2.32, 6.89) 4.05 (2.35, 6.98)
    60–64 0.082 5.83 (3.36, 10.12) 5.96 (3.43, 10.34)
    65–69 0.092 9.12 (5.23, 15.90) 9.27 (5.32, 16.16)
    70–74 0.051 12.55 (7.22, 21.80) 13.10 (7.54, 22.74)
    75–79 0.069 16.80 (9.45, 29.89) 17.36 (9.77, 30.86)
 
SBP < 120 mmHg and DBP < 80 mmHg 0.66 (0.52, 0.85) 0.933 0.68 (0.53, 0.88) 0.69 (0.54, 0.89)
SBP = 120–139 mmHg or DBP = 80–89 mmHg 1.00 1.00 1.00
SBP = 140–159 mmHg or DBP = 90–99 mmHg 1.34 (1.05, 1.69) 0.968 1.34 (1.05, 1.70) 1.34 (1.06, 1.70)
SBP ≥ 160 mmHg or DBP ≥ 100 mmHg or in-medication 1.84 (1.49, 2.25) 0.253 1.81 (1.47, 2.23) 1.84 (1.50, 2.27)
 
Non-HDL-C < 170 mg/dL and LDL-C < 140 mg/dL 1.00 1.00 1.00
Non-HDL-C ≥ 170 mg/dL or LDL-C ≥ 140 mg/dL 1.13 (0.96, 1.33) 0.918 1.19 (1.01, 1.41) 1.18 (1.00, 1.39)
 
HDL-C < 40 mg/dL 1.00 1.00 1.00
HDL-C = 40–59 mg/dL 0.71 (0.58, 0.88) 0.146 0.79 (0.64, 0.97) 0.79 (0.65, 0.98)
HDL-C ≥ 60 mg/dL 0.51 (0.40, 0.65) 0.074 0.66 (0.51, 0.85) 0.66 (0.51, 0.85)
 
Smoking 1.66 (1.39, 1.97) 0.258 1.43 (1.18, 1.74) 1.42 (1.17, 1.72)
Diabetes mellitus 2.36 (1.83, 3.05) 0.168 1.89 (1.45, 2.46) 1.95 (1.50, 2.53)
Urinary protein 1+ or more 1.54 (1.28, 1.86) 0.099 1.23 (1.02, 1.49) 1.25 (1.04, 1.52)
Atrial fibrillation 2.45 (1.31, 4.59) 0.257 2.29 (1.21, 4.33)
Left ventricular hypertrophy 1.94 (1.32, 2.84) 0.179 1.64 (1.11, 2.42)

Abbreviations: SBP, Systolic blood pressure; DBP, Diastolic blood pressure; LDL, Low density lipoprotein; HDL, high-density lipoprotein; Non-HDL, Non- high-density lipoprotein

When each value of blood pressures (SBP and DBP) or lipid profiles (LDL-C and non-HDL-C) belonged to different categories, we adopted the higher category to estimate hazard ratios.