Table 3.

Adjusted odds (95% CI) of any asthma by chronotype (n=413 040)

	Chronotype
	Intermediate chronotype	Definitely a morning person	Definitely an evening person
Total cases (% of total sample size)	15 010 (5.68%)	6786 (6.06%)	2596 (7.06%)
Total sample size	264 279	112 007	36 754
Model 1: Age- and sex-adjusted OR (95% CI)	1 (referent)	1.07 (1.04 to 1.10)	1.27 (1.22 to 1.33)
Model 2: Multivariable adjusted OR (95% CI)	1 (referent)	1.12 (1.04 to 1.22)	1.16 (1.05 to 1.29)
Model 3: Model 2 covariates+sleep duration OR (95% CI)	1 (referent)	1.12 (1.03 to 1.21)	1.16 (1.04 to 1.28)

Model 2 covariates: age, sex, smoking status, smoking pack-years, alcohol status, daily alcohol intake, ethnicity, Townsend Deprivation Index, days exercised (walked, moderate and vigorous), body mass index, length of working week, job asthma risk and job medical required. Model 3 data are adjusted for Model 2 covariates plus sleep duration.