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. 2021 Jan 12;11:631. doi: 10.1038/s41598-020-80152-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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SLCO1B3 staining in representative tissue specimens, and the association between SLCO1B3 expression and the clinical outcome of patients with primary invasive breast cancer. The immunohistochemistry staining of SLCO1B3 on representative tumor specimens and normal breast tissue are shown. Panel (A) shows the negative SLCO1B3 expression in breast cancer tissue (× 200); panel (B,C) show moderately positive (B) and strongly positive (C) SLCO1B3 expression in the breast cancer tissues (× 200). Kaplan–Meier curves for DFS and OS were plotted based on different SLCO1B3 expression levels in all breast cancer patients (D1,D2), or in ER + breast cancer patients (E1,E2) and ER- breast cancer patients (F1,F2).