Table 3.

Univariate and multivariate analysis of OS in 315 breast cancer patients.

Variable	Univariate	Multivariate	Hazard ratio (95% CI)
	P value	P value
Age (> 35 vs. ≤ 35)	0.268
Menopausal status (Post vs. Pre)	0.946
Tumor size (≤ 2 vs. > 2 cm)	0.011	0.014	2.291 (1.179, 4.453)
Lymph node metastasis (Yes vs. No)	< 0.001	< 0.001	4.515 (2.125, 9.594)
Vascular invasion (Yes vs. No)	0.026	0.014	5.989 (1.432, 25.046)
Histological grade (III vs. I–II)	0.010	0.009	2.564 (1.263, 5.205)
ER status (Positive vs. Negative)	0.327
PR status (Positive vs. Negative)	0.026	0.337	0.732 (0.387, 1.384)
Ki-67 (≥ 14% vs. < 14%)	0.658
HER-2 status (Positive vs. Negative)	0.124
SLCO1B3 expression (Positive vs. Negative)	0.015	0.001	0.318 (0.166, 0.610)
Chemotherapy (Yes vs. No)	0.240
Endocrine therapy (Yes vs. No)	0.717

P values less than 0.05 are considered as significant changes.