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. 2021 Jan 12;11:723. doi: 10.1038/s41598-020-80698-z

Table 1.

Baseline clinicopathological characteristics of patients.

Characteristics Total Married Widowed Single Divorced/separated P value
N = 8834 N = 4817 N = 894 N = 1732 N = 1391
Sex  < 0.001
Male(%) 7166 4151 (86.2) 494(55.3) 1417(81.8) 1104 (79.4)
Female(%) 1668 666 (13.8) 400 (44.7) 315(18.2) 287 (20.6)
Age  < 0.001
 < 65(%) 5005 2580 (53.6) 201(22.5) 1298(74.9) 926 (66.6)
 ≥ 65(%) 3829 2237 (46.4) 693(77.5) 434(25.1) 465 (33.4)
Race  < 0.001
White(%) 7132 4103 (85.2) 717(80.2) 1176(67.9) 1136(81.7)
Black(%) 1378 474 (9.8) 153(17.1) 521(30.1) 230(16.5)
Other1(%) 324 240 (5.0) 24(2.7) 35(2.1) 25(1.8)
Grade  < 0.001
Grade I(%) 1490 911 (18.9) 120(13.4) 247(14.3) 212(15.2)
Grade II(%) 5155 2827 (58.7) 524(58.6) 1025(59.2) 779(56.0)
Grade III/ Grade IV(%) 2189 1079 (22.4) 250(28.0) 460(26.5) 400(28.8)
Histological type 0.95
Squamous cell carcinoma(%) 8563 4669 (96.9) 869(97.2) 1679(96.9) 1346(96.8)
Other2(%) 271 148 (3.1) 25(2.8) 53(3.1) 45(3.2)
Surgery  < 0.001
No (%) 5345 2816 (58.5) 599(67.0) 1055(60.9) 875(62.9)
Yes (%) 3489 2001 (41.5) 295(33.0) 677(39.1) 516(37.1)
AJCC stage  < 0.001
I (%) 2885 1906 (39.6) 249(27.9) 394(22.7) 336(24.2)
II (%) 1497 861(17.9) 178(19.9) 232(13.4) 226(16.2)
III (%) 1657 832 (17.3) 189(21.1) 343(19.8) 293(21.0)
IV (%) 2795 1218 (25.2) 278(31.1) 763(44.1) 536(38.5)
Radiotherapy  < 0.001
Yes (%) 2566 1474 (30.6) 213(23.8) 494(28.5) 385(27.7)
No/unknown (%) 6268 3343(69.4) 681(76.2) 1238(71.5) 1006(72.3)
Chemotherapy  < 0.001
Yes (%) 3196 1562 (32.4) 279(31.2) 747(43.1) 608(43.7)
No/unknown (%) 5638 3255(67.6) 615(68.8) 985(56.9) 783(56.3)

Other1 (Asian or Pacific Islander, American Indian/Alaska Native).

Other2 (Neoplasm, malignant; Carcinoma, NOS; Carcinoma, undifferentiated, NOS; Large cell carcinoma, NOS; Large cell neuroendocrine carcinoma; Spindle cell carcinoma, NOS; Pseudosarcomatous carcinoma; Carcinoma, anaplastic, NOS; Non-small cell carcinoma; Small cell carcinoma, NOS; Papillary squamous cell carcinoma; Verrucous carcinoma, NOS; Combined small cell carcinoma; Papillary carcinoma, NOS; Basaloid squamous cell carcinoma; Lymphoepithelial carcinoma; Basaloid carcinoma; Adenocarcinoma, NOS; Scirrhous adenocarcinoma; Adenoid cystic carcinoma; Neuroendocrine carcinoma, NOS; Mucoepidermoid carcinoma; Papillary carcinoma, follicular variant; Adenosquamous carcinoma; Adenocarcinoma with cartilaginous and osseous metaplasia; Adenocarcinoma with neuroendocrine differentiation; Carcinoma in pleomorphic adenoma).