Figure 5.
Mouse xenograft models of human lung (A549) cancer, human cervical (ME-180) cancer, and human ovarian (NIH:OVCAR-3) cancer treated by CDDP or RDM-B (BV10) alone and their combination. (A–C) Tumor growth curves for the A549, NIH:OVCAR-3, and ME-180 models, respectively, where error bars represent the standard error of the mean (s.e.m.). (D) Representative pictures of mice bearing ovarian tumors. The statistical analysis results indicated in (A)–(C) were obtained from either two-way ANOVA (multiple groups in A and C) or unpaired two-tail student t tests (two groups in B): ***, p < 0.001; **, p < 0.01; *, p < 0.05; n.s., nonsignificant (p ≥ 0.05). Statistical analyses were performed with GraphPad Prism 9.0.0 (https://www.graphpad.com/scientific-software/prism/) and Microsoft Excel.