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. 2021 Jan 12;12:340. doi: 10.1038/s41467-020-20403-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Relative percentage of products in the downstream direction (reductive amination/carboxylation) (a), and upstream direction (oxidative deamination/decarboxylation) (b). In both cases, the relative product distribution was maintained after recharging the system with new buffer and substrates. Error bars represent standard errors of the mean taken from three independent repeat experiments (data points plotted as circles for stage 1 and squares after recharging, N = 3).