Table 4.
Key characteristics of liver fibrosis.
| No fibrosis N = 36 |
Fibrosis N = 13 |
p-value | p-value Logistic regression analysis |
|
|---|---|---|---|---|
| Clinical parameters | ||||
| Age (years) | 49.7 | 50.3 | 0.89 | |
| Weight (kg) | 100.8 | 118.3 | 0.003 | |
| BMI (kg/m2) | 34.9 | 38.6 | 0.14 | |
| Waist (cm) | 112.6 | 124.0 | 0.02 | 0.447 |
| Waist to hip ratio | 0.96 | 1.01 | 0.08 | |
| Sex (M/F) | 14/22 | 11/2 | 0.005 | 0.436 |
| Antidiabetic drug (n/total) | 8/36 | 6/13 | 0.10 | |
| Biological results | ||||
| ASAT (UI/L) | 23.8 | 34.2 | 0.04 | 0.111 |
| ALAT (UI/L) | 35.7 | 54.6 | 0.08 | |
| γGT (UI/L) | 46.1 | 52.8 | 0.52 | |
| Fasting glycemia (mg/dL) | 105.2 | 107.0 | 0.81 | |
| Bioimpedance analysis | ||||
| Resistance | 447.2 | 421.5 | 0.29 | |
| Fat free mass (kg) | 63.5 | 76.2 | 0.002 | |
| Total body fat (kg) | 38.1 | 42.1 | 0.33 | |
| CT scan data | ||||
| Subcutaneous fat area (cm2) | 337.5 | 411.3 | 0.23 | |
| Visceral fat area (cm2) | 237.6 | 302.0 | 0.07 | |
| Whole muscle area (cm2) | 165.8 | 199.6 | 0.009 | |
| Skeletal muscle index (cm2/m2) | 57.7 | 64.2 | 0.10 | |
| Skeletal muscle density (HU) | 32.6 | 31.8 | 0.72 | |
| Skeletal muscle density index (HU/cm2) | 0.202 | 0.160 | 0.0004 | 0.014 |
Results are given as mean value (and compared with a bilateral Student-t-test). Number of patients are compared with a chi-squared test. All significant parameters from the univariate analysis (except for collinear values) included in the logistic regression analysis are reported in the last column.
ASAT aspartate aminotransferase, ALAT alanine aminotransferase, BMI body mass index, γGT γ-glutamyl transferase, HU Hounsfield unit.
Significant differences are presented in bold.