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. 2021 Jan 12;11:496. doi: 10.1038/s41598-020-79774-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of the ¹³C NMR data between 5 and briarenolide P²⁷ (carbon chemical shift differences: Δδ_C > 3 ppm in red and Δδ_C between 0.5 to 1.8 ppm in blue), key coupling constants (see reference¹⁸) and NOE correlations in 5. Figures were created with Chemdraw 20.0 and Chem3D v.2020.