Table 4.
Over-representation of genes with a significant association between MDD and GReX or EReX among top N oDEGs.
N = 30 | N = 60 | N = 100 | N = 150 | N = 200 | N = 300 | |
---|---|---|---|---|---|---|
GReX | 1.24E−02 | 1.62E−02 | 7.80E−04 | 3.09E−04 | 1.10E−04 | 2.97E−04 |
EReX | 1.33E−36 | 6.65E−68 | 1.17E−96 | 1.18E−136 | 1.78E−175 | 2.38E-272 |
Hypergeometric tests were used to evaluate the over-representation of genes showing a significant association between MDD and GReX or MDD and EReX among subsets of N oDEGs, ranked by p values of the association test between the observed gene expression and the MDD status, compared to all expressed genes.