Table 2.
Univariate and multivariate logistic regression analyses of factors influencing controlled attenuation parameter values in patients with CHB.
| S0 (n = 3911) | ≥ S1 (n = 1769) | Univariate, OR (95% CI) | P | Multivariate, OR (95% CI) | P | |
|---|---|---|---|---|---|---|
| Age, years | 42.21 ± 11.5 | 43.42 ± 10.4 | 1.010 (1.005–1.015) | < 0.001 | ||
| Male patients, n (%) | 2651 (68.8) | 1422 (80.5) | 1.962 (1.713–2.246) | < 0.001 | ||
| BMI, kg/m2 | 22.78 ± 2.8 | 24.28 ± 3.5 | 1.218 (1.194–1.243) | < 0.001 | 1.142 (1.057–1.234) | 0.001 |
| Waist circumference, cm | 80.14 ± 7.9 | 85.56 ± 8.5 | 1.085 (1.077–1.094) | < 0.001 | ||
| Hip circumference, cm | 92.47 ± 6.3 | 96.67 ± 22.8 | 1.099 (1.088–1.110) | < 0.001 | ||
| ALT, U/L | 31 (21–47) | 39 (28–57) | 1.009 (1.007–1.011) | < 0.001 | 1.011 (1.006–1.017) | < 0.001 |
| AST, U/L | 31 (25–42) | 33 (26–42) | 1.001 (0.998–1.003) | 0.629 | ||
| GLU | 5.61 ± 1.8 | 5.86 ± 3.5 | 1.027 (0.980–1.076) | 0.269 | ||
| TG, mmol/L | 1.16 ± 1.0 | 1.63 ± 1.1 | 1.736 (1.526–1.975) | < 0.001 | 1.537 (1.255–1.881) | < 0.001 |
| Cholesterol, mmol/L | 4.21 ± 1.2 | 4.63 ± 4.1 | 1.185 (1.081–1.299) | < 0.001 | ||
| HDL-C, mmol/L | 1.43 ± 0.46 | 1.41 ± 3.3 | 0.436 (0.341–0.558) | < 0.001 | ||
| LDL-C, mmol/L | 2.34 ± 0.75 | 2.62 ± 1.1 | 1.522 (1.333–1.737) | < 0.001 | 1.887 (1.172–3.034) | 0.011 |
| ALB, g/L | 45.86 ± 5.5 | 46.00 ± 5.1 | 1.005 (0.993–1.018) | 0.427 | ||
| GLB, g/L | 30.47 ± 6.8 | 30.78 ± 7.2 | 1.006 (0.997–1.016) | 0.182 | ||
| TB, μmol/L | 18.20 ± 11.9 | 18.09 ± 14.2 | 0.999 (0.994–1.005) | 0.797 | ||
| DB, μmol/L | 6.34 ± 7.0 | 5.67 ± 4.7 | 0.977 (0.963–0.992) | 0.003 | ||
| GGT, U/L | 24 (16–41) | 28 (18–50) | 1.003 (1.002–1.005) | < 0.001 | ||
| ALP, U/L | 78( 63–97) | 79 (64–97) | 1.001 (0.999–1.003) | 0.350 | ||
| Platelet × 109/L | 118 (79–162) | 124 (84–167) | 1.002 (1.000–1.003) | 0.035 | 1.003 (1.000–1.017) | 0.023 |
| LSM, kPa | 10.16 ± 8.3 | 9.70 ± 7.3 | 0.992 (0.985–1.000) | < 0.001 |
BMI body mass index, ALT alanine aminotransferase, AST aspartate aminotransferase, TB total bilirubin, DB direct bilirubin, TG triacylglycerol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, GGT gamma glutamyltransferase, ALP alkaline phosphatase, LSM liver stiffness measurement, CAP controlled attenuation parameter.