Table 3.
IC50 values for complexes 1–11 in SVG p12 and T98G cell lines (N = 9).
| Complex | IC50 (mM) | |
|---|---|---|
| SVG p12 | T98G | |
| 1 | 2.09 ± 0.15 a | 1.72 ± 0.08 |
| 2 | 2.10 ± 0.12 a | 1.31 ± 0.04 |
| 3 | 1.76 ± 0.07 | 1.17 ± 0.05 |
| 4 | 1.19 ± 0.04 | 1.19 ± 0.04 |
| 5 | 1.63 ± 0.07 | 1.32 ± 0.04 |
| 6 | 2.06 ± 0.08 a | 1.81 ± 0.06 |
| 7 | 1.58 ± 0.04 | 1.20 ± 0.06 |
| 8 | 1.87 ± 0.06 | 1.78 ± 0.04 |
| 9 | 1.98 ± 0.05 | 1.39 ± 0.04 |
| 10 | > 2.00b | > 2.00b |
| 11 | 2.13 ± 0.09a | 2.55 ± 0.33c |
aIC50 values were determined by means of the GraphPad Prism 7 non-linear regression analysis tool.
bValue too large to accurately predict using available data between 62.5 μM and 2 mM.
cValue reported previously (N = 4) in Ref.8.