Figure 9.
Corticosterone effect alcohol-induced dysbiosis of intestinal mycobiome. Adult mice were fed a liquid diet with (EF) or without (PF) ethanol for four weeks. In some groups, animals were injected with corticosterone (CORT) daily. Animals in other groups were injected with the vehicle. Analysis of data from 16S rRNA-sequencing of fecal samples from different groups of mice is presented. (A) Fungal phylum is displayed in each group. (B) Fungal α-diversity calculated by Chao1. (C) Principal coordinate analysis was used to visualize β-diversity in fungal populations with Jaccard dissimilarity. (D) Significantly altered fungal genus are displayed by ANOVA. *P < 0.05; **P < 0.01; ***P < 0.005.