Table 1. Study characteristics.
Study | Year | Region | Age (years) | Patients | M/F | Patients with KIT mutations | Patients with WT KIT | Patients with t(8;21) | Patients with inv(16) |
---|---|---|---|---|---|---|---|---|---|
Goemans | 2005 | Germany/Netherlands | 0–18 | 27 | NA | 11 | 16 | 16 | 11 |
Shimada | 2006 | Japan | 7.5# (2–15) | 46 | NA | 8 | 38 | 46 | – |
Shih | 2008 | Taiwan | <17 | 41 | NA | 17 | 24 | 28 | 13 |
Pollard | 2010 | America | 11.8# (0.6–19.6) | 203 | 106/97 | 38 | 165 | 113 | 90 |
Park | 2011 | Korea | 4–12 | 16 | 10/6 | 7 | 9 | 16 | – |
Manara | 2014 | Italy | NA | 88 | NA | 20 | 68 | 61 | 27 |
Qin | 2014 | China | 11# (0.5–14) | 53 | NA | 24 | 29 | 42 | 11 |
Klein | 2015 | Netherlands | 9.2*±4.2 | 222 | 123/99 | 53 | 169 | 222 | – |
Tokumasu | 2015 | Japan | NA | 138 | NA | 58 | 80 | 107 | 31 |
Badr | 2018 | Egypt | 6# (1–16) | 34 | 21/13 | 5 | 29 | 22 | 12 |
Chen | 2018 | China | 7# | 50 | 31/19 | 15 | 35 | 44 | 6 |
Tarlock | 2019 | America | 0.33–22.76 | 205 | 103/102 | 63 | 142 | 109 | 96 |
#Median age; *Mean age. WT, wild type.