Table 2. Relationship between hsa_circ_0043278 expression and clinicopathologic features in breast cancer patients.
| Characteristics | No. of cases [%] | Mean ± SD | P value |
|---|---|---|---|
| Age (years) | |||
| ≥60 | 12 [24] | 0.09256±0.108 | 0.6296 |
| <60 | 38 [76] | 0.1315±0.2794 | |
| Diameter (cm) | |||
| <2 | 5 [10] | 0.1158±0.08635 | 0.5535 |
| 2–5 | 38 [76] | 0.1185±0.2712 | |
| ≥5 | 7 [14] | 0.1465±0.2143 | |
| Lymphatic metastasis | |||
| N0 | 30 [60] | 0.173±0.3111 | 0.0201 |
| N1–3 | 20 [40] | 0.04591±0.04019 | |
| Pathological type | |||
| Ductal carcinoma in situ | 6 [12] | 0.3096±0.2705 | 0.0021 |
| Invasive ductal carcinoma | 40 [80] | 0.09771±0.2477 | |
| Others | 4 [8] | 0.08544±0.102 | |
| Histological grade (invasive ductal carcinoma, n=40) | |||
| I | 3 [7.5] | 0.1013±0.04939 | 0.0777 |
| II | 33 [82.5] | 0.1062±0.2718 | |
| III | 4 [10] | 0.0248±0.01611 | |
| Estrogen receptor | |||
| Absent | 9 [18] | 0.2298±0.5058 | 0.9209 |
| Present | 41 [82] | 0.09853±0.1464 | |
| Progesterone receptor | |||
| Absent | 14 [28] | 0.16±0.4087 | 0.3296 |
| Present | 36 [72] | 0.1074±0.1541 | |
| HER-2 | |||
| Negative | 8 [16] | 0.1288±0.1254 | 0.3673 |
| 1+ | 17 [34] | 0.09135±0.1397 | |
| 2+ | 17 [34] | 0.1892±0.3916 | |
| 3+ | 8 [16] | 0.03849±0.02715 | |
| Ki 67 | |||
| <14% | 6 [12] | 0.3224±0.6106 | 0.2705 |
| >14% | 44 [88] | 0.09486±0.1441 | |
HER-2, human epidermal growth receptor 2.