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. 2020 Dec;9(6):2175–2186. doi: 10.21037/gs-20-811

Table 3. Relationship between CA125, CK7, CK20, and ER expressions and clinicopathological features.

Variable n CA125 Positive rate (%) P value CK7 Positive rate (%) P value CK20 Positive rate (%) P value ER Positive rate (%) P value
+ + + +
Age (years) <0.05 <0.05 <0.05 <0.05
   <50 64 2 16 25 1 14 21.9 9 2 3.1 20 24 37.5
   ≥50 189 4 29 15.3 1 33 17.9 23 2 1.1 37 54 28.6
Pathological type 0.3192 0.0259
   Serous 86 0 11 12.8 1 8 9.3 3 0 0 0.5460 19 33 38.4 0.1430
   Mucinous 16 1 2 12.5 1 2 12.5 2 1 6.3 7 2 12.5
   Endometrioid 15 0 3 20 0 3 20 2 0 0 3 4 26.7
   Others 136 5 28 20.6 0 34 25 25 3 2.2 28 33 24.3
Tissue differentiation 0.0773 <0.05 <0.05 0.4771
   High 2 0 0 0 0 0 0 0 0 0 1 1 50
   Moderate 5 0 0 0 0 0 0 0 0 0 0 2 40
   Low 111 4 23 20.7 0 28 25.2 17 1 0.9 26 36 32.4
FIGO stage 0 <0.05 1.0000 1.0000 <0.05
   I‒II 55 2 5 9.1 0 10 18.2 6 1 1.8 17 10 18.2
   III‒IV 198 4 39 19.7 2 37 18.7 26 3 1.5 40 63 31.8
Residual lesions 0.6615 <0.0001 0.4593 0.4082
   0 53 0 5 9.4 0 7 13.2 3 1 1.9 13 17 32.1
   1 174 5 35 20.1 1 35 20.1 25 2 1.1 40 54 31.0
   2 26 1 5 19.2 5 1 3.8 4 1 3.8 7 4 15.4

−, negative; +, positive. ER, estrogen receptor; FIGO, federation of international gynecology and obstetrics.