Figure 1.
siRNA-mediated depletion of FL2 enhances corneal re-epithelialization. (A) Images of fluorescein-stained eyes day of and 8 days after injury. (B) Plots showing the kinetics of corneal re-epithelialization over 10 days with prednisone (blue line), 10 µM control-NPsi (red line), and 10 µM FL2-NPsi (green line). (C) Plots showing the kinetics of corneal re-epithelialization over 10 days with prednisone (blue line), 20 µM control-NPsi (red line), and 20 µM FL2-NPsi (green line). Data were pooled from multiple independent assays from corneas with alkaline injuries. The data for every time point were assessed using 1-way ANOVA and the levels of significance shown (**** = p < 0.0001; *** = p < 0.001; ** = p < 0.01; * = p < 0.05; n.s., not significant).