Table 3.
Replication findings for single variant test.
| SNV, coded allele (gene)/ Replication study |
Number | Minor Allele Count | Beta (SE) | p | Direction of effect consistency |
|---|---|---|---|---|---|
| rs180996919, C (PRKAA2) | |||||
| THRV | 1,113 | 4 | 1.317 (2.853) | 0.64 | No |
| BBJ | 1,524 | 6 | −0.114 (0.305) | 0.71 | Yes |
| rs116951054, A (METTL8) | |||||
| THRV | 1,113 | 7 | −0.876 (2.039) | 0.67 | No |
| BBJ | 1,524 | 4 | 0.274 (0.365) | 0.45 | Yes |
| rs539182790, G (MATK) | |||||
| HCHS/SOL Hispanics* | 6,767 | 201 | −0.963 (1.059) | 0.36 | Yes |
| Full Pima Indians | 1,438 | 60 | −0.013 (0.053) | 0.81 | Yes |
| Non-Full Pima Indians | 757 | 17 | 0.080 (0.077) | 0.30 | No |
| FIND American Indians | 836 | 56 | 0.026 (0.076) | 0.73 | No |
BBJ, BioBank Japan; FIND, Family Investigation of Nephropathy and Diabetes; HCHS/SOL, Hispanic Community Health Study/Study of Latinos; NA, not available.
⁎
TOPMed freeze 5b imputed data.