Table 2.
Characteristics of eligible studies
| First author (location; year) | RCT design (blinding) | Population | Sex | Sample size (Q10/placebo) | Duration (weeks) | Dose of Q10 (mg/day) | Outcomes |
|---|---|---|---|---|---|---|---|
| Abdollahzad (Iran; 2015) | Parallel (double) | Rheumatoid arthritis | Both | 22/23 | 8 | 100 | Weight, BMI |
| Rahmani (Iran; 2018) | Parallel (double) | Polycystic ovary syndrome | Woman | 20/20 | 12 | 100 | Weight, BMI |
| Fallah (Iran; 2018) | Parallel (double) | Hemodialysis patients | Both | 30/30 | 12 | 120 | Weight, BMI |
| Gholami (Iran; 2018) | Parallel (double) | Type 2 diabetes | Woman | 34/34 | 12 | 100 | Weight, BMI, WC |
| Attar (Iran; 2015) | Parallel (double) | Type 2 diabetes | Both | 31/33 | 12 | 200 | Weight, BMI, WC |
| Jafarvand (Iran; 2016) | Parallel (double) | Nonalcoholic fatty liver disease | Both | 20/21 | 4 | 100 | BMI, WC |
| Zhang (China; 2018) | Parallel (double) | Dyslipidemia | Both | 51/50 | 24 | 120 | WC, weight, BMI |
| Mori (Australia; 2009) | Parallel (double) | Chronic kidney disease | Both | 21/15 | 8 | 200 | Weight |
| Henriksen (Denmark; 1999) | Parallel (double) | Type 1 diabetes mellitus | Both | 17/17 | 12 | 100 | Weight |
| Moazen (Iran; 2015) | Parallel (single) | Type 2 diabetes | Both | 26/26 | 8 | 100 | Weight, BMI |
| Ericsson (Finland; 1999) | Parallel (double) | Type 2 diabetes | Both | 12/11 | 24 | 100 | BMI |
| Dai (Hong Kong; 2011) | Parallel (double) | Ischemic left ventricular systolic dysfunction | Both | 28/28 | 8 | 300 | BMI |
| Farsi (Iran; 2016) | Parallel (double) | Nonalcoholic fatty liver disease | Both | 20/21 | 12 | 100 | Weight, BMI, WC |
| Mohseni (Iran; 2015) | Parallel (double) | Acute myocardial infarction | Both | 26/26 | 12 | 200 | Weight, BMI |
| Gholnari (Iran; 2018) | Parallel (double) | Diabetic nephropathy | Both | 25/25 | 12 | 100 | Weight, BMI |
| Hodgson (Australia; 2002) | Parallel (double) | Type 2 diabetes | Both | 19/18 | 12 | 200 | Weight |
| Izadi (Iran; 2018) | Parallel (double) | Polycystic ovary syndrome | Woman | 22/21 | 8 | 200 | Weight, BMI |
| Shojaei (Iran; 2011) | Parallel (double) | Hemodialysis patients | Both | 13/13 | 12 | 100 | BMI |
| Nadjarzadeh (Iran; 2011) | Parallel (double) | Idiopathic oligoasthenoteratozoospermia | Man | 23/24 | 12 | 200 | BMI |
| Raygan (Iran; 2016) | Parallel (double) | Metabolic syndrome | Both | 30/30 | 8 | 100 | Weight, BMI |
RCT=Randomized controlled trial; BMI=Body mass index; WC=Waist circumference