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Shift distribution of patient numbers by GPR124 c.3587G>A mutation or by the top five Wnt signaling genetic variants. Number of patients (%) in each group with GPR124 c.3587G>A mutation (A) or with alleles of the top five Wnt signaling genetic variants enriched in the PH patients (WNT7A rs2163910 and rs1124480, GPR124 rs61738775, rs146016051, and rs75336000; 2 alleles/variant, 10 alleles totally) (B) was calculated
