Birth hospitalizations refer to liveborn infant discharge records; delivery hospitalizations refer to maternal discharge records, regardless of pregnancy outcome. Percent change reflects the overall or total percentage change between the 2 end points [(2017 – 2010)/2010 × 100]; The International Classification of Disease, 10th Revision, Clinical Modification, implemented in October 2015, expanded maternal opioid-related diagnoses to include new codes for long-term use of opioid medications and unspecified opioid use in addition to opioid dependence and abuse. Source: Agency for Healthcare Research and Quality, Healthcare Cost and Utilization Project, State Inpatient Databases, 47 States and the District of Columbia (excludes Alabama, Idaho and New Hampshire; Delaware, District of Columbia, and North Dakota did not participate in 2010).