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. 2021 Jan 9;27(1):134–144. doi: 10.1111/cns.13580

FIGURE 3.

FIGURE 3

Perampanel attenuates oxidative stress and neuroinflammation. (A and B) Perampanel inhibits lipid peroxidation, as evidenced by reduced levels of MDA (A) and (4‐HNE). (C and D) Perampanel reduces IL‐1β level after TNI (C) and glutamate treatment (D). (E and F) Perampanel reduces IL‐6 level after TNI (E) and glutamate treatment (F). Error bars indicate SEM (n = 6). # p < 0.05 vs. Control group. *p < 0.05 vs. TNI group. & p < 0.05 vs. Glu group