Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 12;12:338. doi: 10.1038/s41467-020-20565-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — a Proportion of subjects with detected mCA increases with age. b Classification of events by copy number states. logR: log₂ ratio of the coverage depth between analyzed sample and normal comparison. logOR: log allelic ratio between major and minor alleles in heterozygous SNP loci. Events are colored by inferred alteration type. c Number of subjects with 1, 2, or 3+ mCAs. d Cell fraction of detected aberrant clones stratified by alteration type. Numbers below the violins indicate the minimum. e Genome-wide distributions of detected mCAs. f Proportion of subjects with mCA among major cancer types. Squares: observed incidence. Blue circles: expected incidence. 95% CI are shown in black. Number of patients are displayed in the middle. Source data are provided as a Source Data file.