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. 2021 Jan 12;12:295. doi: 10.1038/s41467-020-20527-z

Fig. 2. circNDUFB2 inhibits proliferation and metastasis of NSCLC cells in vitro and in vivo.

Fig. 2

a, b Cell proliferation assays for NSCLC cells with circNDUFB2 overexpression or knockdown. n = 5 biologically independent samples. c, d Colony formation assays for NSCLC cells with circNDUFB2 overexpression or knockdown. n = 3 biologically independent samples. e, f Migration and invasion assays for NSCLC cells with circNDUFB2 overexpression or knockdown. n = 3 biologically independent samples. Scale bar = 100 μm. g The volume and weight of subcutaneous xenograft tumors (n = 7 mice per group). h Representative pictures of the lung metastases in nude mice by H&E staining (n = 7 mice per group). C cancer site. Scale bar = 100 μm. Data are presented as mean ± s.d. P values are calculated by unpaired two-sided t-test in a, b and c–h.