Table 3:

Association of demographics and GA domains with number of ICI cycles received

		ICI Cycles Received
Variable		# of observations	Median (IQR limits)	Test* p-value
Age at GA (years)	≤76	13	2.0 (2.0–6.0)	0.80
	>76	15	5.0 (1.0–15.0)
Timing of GA	Immediately prior to ICI	15	2.0 (1.0–7.0)	0.44
	Immediately prior to chemotherapy but prior to ICI	13	6.0 (1.0–15.0)
ECOG Performance Status	0–1	11	3.0 (2.0–19.0)	0.55
	2–3	17	4.0 (1.0–7.0)
Any ADL impairment	No	7	7.0 (2.0–19.0)	0.14
	Yes	7	2.0 (1.0–15.0)
	Unknown	14
Any IADL impairment	No	12	7.0 (2.5–25.5)	0.02
	Yes	12	2.0 (1.0–5.0)
	Unknown	4
Falls (in past year)	No	19	3.0 (1.0–7.0)	0.75
	Yes	9	5.0 (2.0–15.0)
SPPB impairment	No	3	4.0 (2.0–7.0)	1.00
	Yes	21	5.0 (1.0–16.0)
	Unknown	4
Comorbidities	≤4	8	7.0 (3.5–16.0)	0.27
	>4	12	2.0 (1.5–6.0)
	Unknown	8
Hearing impairment	Excellent/Good	16	6.0 (1.5–15.5)	0.84
	Fair/Poor	9	3.0 (2.0–6.0)
	Unknown	3
Vision impairment	Excellent/Good	18	4.0 (1.0–7.0)	0.34
	Fair/Poor	7	6.0 (2.0–32.0)
	Unknown	3
BOMC impairment	No	17	4.0 (2.0–7.0)	0.98
	Yes	10	3.5 (1.0–17.0)
	Unknown	1
Presence of weight lossa	No	12	6.0 (2.0–16.5)	0.06
	Yes	11	2.0 (1.0–6.0)
	Unknown	5
Patient-reported sarcopenia	No	10	7.0 (3.0–17.0)	0.13
	Yes	8	2.0 (1.0–10.0)
	Unknown	10
GDS Score impairment	No	21	4.0 (2.0–7.0)	0.71
	Yes	7	2.0 (1.0–15.0)
VES-13 impairment	No	8	5.5 (1.5–13.0)	0.80
	Yes	13	3.0 (2.0–15.0)
	Unknown	7

^*Wilcoxon Rank Sum Test

Abbreviations: ADL, Activities of Daily Living; BOMC, Blessed Orientation-Memory-Concentration Test; CR, complete response; ECOG, Eastern Collaborative Oncology Group; GA, geriatric assessment; IADL, Instrumental Activities of Daily Living; SPPB, Short Physical Performance Battery Test; VES-13, Vulnerable Elders Survey-13

^aDefined as more than 5%